Mushonga wezvipembeneneKusagona kurwisa ma arthropods anotapurirana zvirwere zvine chekuita nekurima, zvemhuka uye hutano hweveruzhinji kunokanganisa zvirongwa zvepasi rose zvekudzora mavectors. Zvidzidzo zvekare zvakaratidza kuti ma arthropods anosveta ropa anowana huwandu hwakawanda hwerufu kana akadya ropa rine zvinodzivirira 4-hydroxyphenylpyruvate dioxygenase (HPPD), iyo enzyme yechipiri mu metabolism ye tyrosine. Chidzidzo ichi chakaongorora kushanda kwe β-triketone HPPD inhibitors pakurwisa mhando nhatu huru dzezvirwere dzinopararira, kusanganisira umhutu hunotapurirana zvirwere zvekare zvakaita semarariya, hutachiona hunodzokororwa senge dengue neZika, uye mavhairasi ari kubuda akadai seOropuche neUsutu viruses.
Musiyano uripo pakati penzira dzekushandisa mushonga wepamusoro, wetarsal newachivharo, nzira dzekushandisa, kuendesa zvipembenene uye nguva yekushanda.
Zvisinei, pasinei nemusiyano wekufa pakati peNew Orleans neMuheza pahuwandu hwepamusoro, huwandu hwese hwese hwaive hwakanyanya kushanda muNew Orleans (hunogona kubatwa nechirwere) kupfuura muMuheza (husingapindi mushonga) kwemaawa makumi maviri nemana.
Zvakawanikwa zvedu zvinoratidza kuti nitisinone inouraya umhutu hunosveta ropa kuburikidza nekubatana kwe transtarsal, nepo mesotrione, sulfotrione, uye tepoxiton hazvidaro. Nzira iyi yekuuraya haisaruri pakati pemhando dzeumhutu dzinonzwa kana kuti dzisingapindi zvakanyanya kune mamwe marudzi emishonga yezvipembenene, kusanganisira pyrethroids, organochlorines, uye pamwe carbamates. Uyezve, kushanda kwe nitisinone mukuuraya umhutu kuburikidza nekusveta epidermal hakugumiri kumarudzi eAnopheles, sezvakaratidzwa nekushanda kwayo pakurwisa Strongyloides quinquefasciatus naAedes aegypti. Data redu rinotsigira kudiwa kwekutsvaga kwakawedzerwa kuti kuwedzere kusveta kwe nitisinone, pamwe kuburikidza nekuwedzera makemikari ekusveta epidermal kana kuwedzera zvimwe zvinobatsira. Kuburikidza nemaitiro ayo matsva ekushanda, nitisinone inoshandisa maitiro ekusveta ropa eumhutu hwechikadzi. Izvi zvinoita kuti ive mukana wekuwana mishonga mitsva inosara mumba uye mambure ekuuraya zvipembenene anogara kwenguva refu, kunyanya munzvimbo uko nzira dzechinyakare dzekudzivirira umhutu dzisingashande nekuda kwekubuda nekukurumidza kwekusadzivirira pyrethroid.
Nguva yekutumira: Nyamavhuvhu-06-2025