Florfenicolis a synthetic monofluoro derivative of thiamphenicol, the molecular formula is C12H14Cl2FNO4S, white or off-white crystalline powder, inonhuhwirira, inonyungudika zvishoma mumvura uye chloroform, inonyungudika zvishoma muglacial acetic acid, inonyungudika muMethanol, ethanol.Mushonga mutsva wakafaranuka wechloramphenicol wekushandisa veterinary, wakagadzirwa zvakabudirira mukupera kwema1980.
Wakatanga kutengeswa kuJapan muna 1990. Muna 1993, Norway yakabvumira mushonga uyu kurapa furuncle yesalmon.Muna 1995, France, United Kingdom, Austria, Mexico neSpain dzakabvumira mushonga uyu kurapa bovine kufema bhakitiriya zvirwere.Inotenderwawo kushandiswa sekuwedzera kwekudya kwenguruve muJapan neMexico kudzivirira nekurapa zvirwere zvebhakitiriya munguruve, uye China ikozvino yatendera mushonga uyu.
Mushonga unorwisa mabhakitiriya, unogadzira yakakura-spectrum bacteriostatic effect nekudzivisa basa re peptidyltransferase, uye ine yakakura antibacterial spectrum, kusanganisira zvakasiyana-siyana.Gram-positiveuye mabhakitiriya asina kunaka uye mycoplasma.Mabhakitiriya anonzwa anosanganisira bovine uye porcine Haemophilus,Shigella dysentery, Salmonella, Escherichia coli, Pneumococcus, Influenza bacillus, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, etc. kukura kwepeptidase, kunotadzisa kuumbwa kweketani dzepeptide, nokudaro kudzivirira mapuroteni synthesis, kuzadzisa chinangwa cheAntibacterial.Ichi chigadzirwa chinokurumidza kutorwa nemuromo wekutonga, kuparadzirwa zvakanyanya, chine hafu yehupenyu hurefu, huwandu hwemishonga yeropa, uye nguva yakareba yekugadzirisa zvinodhaka.
Mumakore achangopfuura, mapurazi akawanda maduku uye epakati penguruve akashandisa florfenicol kurapwa pasinei nemamiriro ezvinhu enguruve, uye akashandisa florfenicol semishonga yemashiripiti.Kutaura zvazviri, izvi zvine ngozi zvikuru.Iine maitiro akanaka ekurapa kwezvirwere zvenguruve zvinokonzerwa neGram-positive uye yakaipa mabhakitiriya uye mycoplasma, kunyanya mushure mekusanganiswa kweflorfenicol uye doxycycline, mhedzisiro yacho inowedzera, uye inoshanda mukurapa porcine thoracic swine atrophic rhinitis chain.Cocci, nezvimwewo zvine kurapa kwakanaka.
Zvisinei, chikonzero nei zvine ngozi kushandisa florfenicol nguva dzose ndechokuti kune zvakawanda zvinokonzerwa neflorfenicol, uye kushandiswa kwenguva refu kweflorfenicol kunokuvadza kupfuura kunaka.Somuenzaniso, shamwari dzenguruve hadzifaniri kufuratira pfungwa idzi.
1. Kana pane zvirwere zvehutachiona zvakadai se pseudorabies swine fever ne blue ear ring mupurazi yenguruve, kushandiswa kweflorfenicol yekurapa kunowanzova kupindirana kwezvirwere izvi zvehutachiona, saka kana zvirwere zviri pamusoro zvakatapukirwa uye zvichizotevera Kana uchinge wabatwa nehutachiona. zvimwe zvirwere zvenguruve, usashandise florfenicol pakurapa, zvichawedzera chirwere chacho.
2. Florfenicol ichapindira nehematopoietic system yedu uye inodzivisa kugadzirwa kwemasero matsvuku eropa mumapfupa emapfupa, kunyanya kana nguruve dzedu dzinoyamwisa dzine kutonhora kana kuzvimba.Nguruve yebvudzi ruvara haisi yakanaka, yakakangwa bvudzi, asiwo inoratidza zviratidzo zvekushaya ropa, ichaitawo kuti nguruve isadya kwenguva refu, ichiumba nguruve yakaoma.
3. Florfenicol is embryotoxic.Kana florfenicol inowanzoshandiswa panguva yekuzvitakura mumhodzi, iyo inoguma yenguruve ichakundikana.
4. Kushandiswa kwenguva refu kweflorfenicol kuchakonzera zvirwere zvepamuviri uye manyoka munguruve.
5. Zviri nyore kukonzera chirwere chechipiri, zvakadai se exudative dermatitis inokonzerwa nehutachiona hwe staphylococcus munguruve kana chirwere chechipiri cheimwe fungal dermatitis.
Kupfupisa, florfenicol haifanirwe kushandiswa seyakajairwa mushonga.Patinoshandisa mamwe maantibioti asina kunaka uye ari mune yakasanganiswa pfungwa (kudzinga hutachiona), tinogona kushandisa florfenicol uye doxycycline parutivi.Acupuncture inoshandiswa kurapa zvirwere zvisingagoneki, uye haina kukurudzirwa kune mamwe mamiriro ezvinhu.
Nguva yekutumira: Jul-14-2022