Takayera huwandu hweweti hwe3-phenoxybenzoic acid (3-PBA), pyrethroid metabolite, muvanhu vekuKorea 1239 vekumaruwa nemumaguta. Takaongororawo pyrethroid exposure tichishandisa mubvunzo wedata source;
Mushonga wemumbazvipfapfaidzo ndiwo sosi huru yekuratidzwa munharaunda kune pyrethroids pakati pevakuru vakura muSouth Korea, yambiro nezvekuda kwekutonga kwakanyanya kwezvakatipoteredza izvo zvinogara zvichifumurwa mapyrethroids, kusanganisira zviputi zvezvipembenene.
Nezvikonzero izvi, kudzidza mhedzisiro yepyrethroids muhuwandu hwevanhu vakura kunogona kuve kwakakosha muKorea pamwe nekune dzimwe nyika dzine vanhu vakura vari kukurumidza kukura. Zvisinei, kune nhamba shoma yezvidzidzo zvinoenzanisa pyrethroid exposure kana 3-PBA mazinga muvakuru vakuru mumaruwa kana mumaguta, uye zvidzidzo zvishomanana zvinoshuma nzira dzingangove dzakasvibiswa uye zvinogona kubuda.
Naizvozvo, isu takayera 3-PBA mazinga mune weti samples dzevanhu vakura muKorea uye tikaenzanisa 3-PBA kutariswa muweti yevanhu vekumaruwa nevemudhorobha vakura. Pamusoro pezvo, takaongorora chikamu chinopfuura miganhu iripo kuona kuratidzwa kwepyrethroid pakati pevakuru vakuru muKorea. Isu takaongorora zvakare zvingangove zviwanikwa zve pyrethroid kuratidzwa tichishandisa mibvunzo uye tikaibatanidza neweti 3-PBA mazinga.
Muchidzidzo ichi, takayera weti 3-PBA mazinga muvakuru vekuKorea vanogara kumaruwa nemumaguta uye takaongorora hukama huripo pakati pezvingangove zvichibva pakuratidzwa kwepyrethroid uye weti 3-PBA mazinga. Isu takasarudzawo chikamu chekuwedzeredza kwemiganhu iripo uye yakaongororwa pakati- uye intra-munhu mutsauko mu3-PBA mazinga.
Muchidzidzo chakambobudiswa, takawana kuwirirana kwakakosha pakati peurinary 3-PBA mazinga uye kuderera kwemapapu ekushanda mumaguta evakuru muSouth Korea [3]. Nekuti takaona kuti vanhu vakuru vekuKorea vakura mumaguta vakaratidzirwa kune yakakwira pyrethroids muchidzidzo chedu chekare [3], isu takaramba tichienzanisa weti 3-PBA mazinga evakuru vekumaruwa nevemudhorobha kuti vaongorore huwandu hwekuwedzeredza kwepyrethroid. Ichi chidzidzo chakabva chaongorora zvingangoitika zve pyrethroid exposure.
Chidzidzo chedu chine masimba akati wandei. Isu takashandisa zviyero zvakadzokororwa zveurinary 3-PBA kuratidza kuratidzwa kwepyrethroid. Iyi longitudinal panel dhizaini inogona kuratidza shanduko yenguva mukuratidzwa kwepyrethroid, iyo inogona kuchinja nyore nekufamba kwenguva. Mukuwedzera, nechirongwa ichi chekudzidza, tinogona kuongorora nyaya imwe neimwe sekutonga kwake uye kuongorora migumisiro yenguva pfupi yepirethroid exposure uchishandisa 3-PBA se covariate yenguva yenguva mukati mevanhu. Pamusoro pezvo, isu takanga tiri vekutanga kuziva zvakatipoteredza (zvisiri zvebasa) zvitubu zvekuratidzwa kwepyrethroid muvakuru vakuru muKorea. Zvisinei, kudzidza kwedu kunewo ganhuriro. Muchidzidzo ichi, takaunganidza ruzivo rwekushandiswa kwemishonga inouraya zvipembenene tichishandisa mibvunzo, saka nguva yenguva pakati pekushandiswa kwemishonga yekuuraya zvipembenene uye kuunganidza weti haina kukwanisa kuzivikanwa. Kunyangwe maitiro ekuzvibata ekushandiswa kwepfapfaidzo yezvipembenene asingashanduki nyore nyore, nekuda kwekukurumidza metabolism yepyrethroids mumuviri wemunhu, nguva yenguva pakati pekushandiswa kwepfapfaidzo yezvipembenene uye kuunganidza weti inogona kukanganisa zvakanyanya weti 3-PBA. Pamusoro pezvo, vatori vechikamu vedu vaive vasingamiriri sezvo takangotarisa kune imwe chete yekumaruwa uye imwe yedhorobha, kunyangwe nhanho dzedu dze3-PBA dzaive dzakaenzana nedzakayerwa muvakuru, kusanganisira vakuru vakuru, muKoNEHS. Nokudaro, mamwe maturusi ezvakatipoteredza ane chokuita nekuputika kwepyrethroid anofanirwa kuenderera mberi achidzidzwa mumumiririri wevanhu vakwegura.
Nekudaro, vanhu vakuru muKorea vanoratidzirwa kune yakanyanya kuwanda kwepyrethroids, nekushandiswa kwezvipembenene zvekupfapfaidza kuri iko honzeri yekufumurwa kwezvakatipoteredza. Nekudaro, kumwe kutsvagisa kunodiwa pamabviro ekufumurwa kwepyrethroid pakati pevakuru vakura muKorea, uye kutonga kwakasimba pazvinhu zvinogara zvichifumurwa zvakatipoteredza, kusanganisira kushandiswa kwezvipembenene zvekupfapfaidza zvipembenene, zvinodiwa kuchengetedza vanhu vanobatwa nepyrethroids, kusanganisira kusangana nemakemikari ezvakatipoteredza. vanhu vachembera.
Nguva yekutumira: Sep-27-2024