Maitiro ekuita fluconazole

Fluoxapyr inonzi carboxamidefungicideyakagadzirwa neBASF.Iine mabasa akanaka ekudzivirira uye ekurapa.Inoshandiswa kudzivirira uye kudzora yakakura-spectrum fungal zvirwere, angangoita 26 marudzi ezvirwere zvefungal.Inogona kushandiswa zvirimwa zvingangosvika zana, sezvirimwa zvezviyo, nyemba, zvirimwa zvemafuta, nzungu, pome nematombo miti yemichero, midzi uye tuber miriwo, miriwo yemichero nedonje, mashizha kana mbeu kurapwa.Fluoxafenamide is succinate dehydrogenase inhibitor uye yakanakisa fungicide yakagadzirwa mumakore achangopfuura.
Physicochemical properties ye fluconazole

Fluconazole Chemical Name: 3-(difluoromethyl)-1-methyl-N-(3′,4′,5′-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide, 3-(difluoro Methyl)-1- methyl-N-(3′,4′,5′-trifluorobiphenyl-2-yl) -1H-pyrazole-4-carboxamide;Nhamba yeCAS: 907204-31-3, Molecular formula: C18H12F5N3O.Molecular uremu: 381.31 g/mol.Fluoxapyr (kuchena 99.3%) ichena kune beige yakasimba, isinganhuhwi, inonyunguduka 156.8 ℃, hukama hwehukama (20 ℃) ​​1.42 g/mL, inoora paanenge 230 ℃, vapor pressure (inofungidzirwa): 2.7 × 10- 9 Pa 20°C), 8.1×10-9 Pa (25°C);Nguva dzose yaHenry: 3.028 × 10-7 Pa · m3 / mol.Solubility (20℃): mvura 3.88 mg/L (pH 5.84), 3.78 mg/L (pH 4.01), 3.44 mg/L (pH 7.00), 3.84 mg/L (pH 9.00);organic solvent (technical kuchena 99.2) %) (g/L, 20℃): acetone>250, acetonitrile 167.6±0.2, dichloromethane 146.1±0.3, ethyl acetate 123.3±0.2, methanol±0.40±0.4. octanol 4.69±0.1 , n-heptane 0.106 ± 0.001.n-octanol-water partition coefficient (20°C): deionized water log Kow 3.08, log Kow 3.09 (pH 4), log Kow 3.13 (pH 7), log Kow 3.09 (pH 9), avhareji yedanda Kow (3.10±0.02) ) .Yakagadzikana mune aqueous solution papH 4, 5, 7, 9 pasi perima uye sterile mamiriro.Kuvhenekera kwakagadzikana.

Toxicity yeFluoxafen

Acute oral toxicity mumakonzo (mukadzi) wepakutanga mushonga we fluconazole: LD50≥2,000 mg/kg, acute dermal toxicity mumakonzo (murume nemukadzi): LD50> 2,000 mg/kg, acute inhalation toxicity mumakonzo (murume nemukadzi) : LC50＞5.1 mg/L;kushatirwa kuduku kumaziso etsuro uye ganda retsuro;hapana sensitization kune guinea pig ganda.Hapana carcinogenicity, hapana teratogenicity, hapana mhedzisiro pakubereka, hapana genotoxicity, neurotoxicity uye immunotoxicity.
Muchetura kushiri LD50＞2,000 mg/kg, huturu hweDaphnia 6.78 mg/L (48 h), huturu hwehove hunotyisa (96 h) LC50 0.546 mg/L, huturu hwemvura kumhuka dzisina mapfupa emumvura (48 h) 6 EC750. mg/L, huturu hunotyisa kune algae (72 h) EC50 0.70 mg/L, acute kubata muchetura kune nyuchi (48 h) LD50>100 μg/nyuchi, acute mumuromo huturu kune nyuchi (48 h) LD50>110.9 μg/nyuchi, huturu hwehupfu hwemakonye iLC50>1,000 mg/kg (mazuva gumi nemana).Kubva pane data iri pamusoro, zvinogona kuonekwa kuti Fluoxafen ine chepfu kune zvipenyu zvemvura uye ine yakaderera chepfu kune zvimwe zvipenyu zvinobatsira.

Nzira yekuita yefluoxafen

Fluoxafenamide is succinate dehydrogenase inhibitor, iyo inoshanda pa succinate dehydrogenase mumitochondrial breathing chain complex II kuvharidzira basa rayo, nokudaro ichidzivisa kumera kwefungal pathogen spores, kukura kwegerm tubes uye mycelium.

Fluconazole kudzora zvinhu

Fluoxamid inoshanda zvakanyanya, yakakura-spectrum, yakasimba, inosarudza, ine yakanakisa systemic conductivity, uye inoshingirira kukukurwa kwemvura.Inogona kunyatso kudzora zviyo, soya bhinzi, chibage, mhodzi dzechibharo, miti yemichero, miriwo, uye shuga beet kuburikidza nefoliar uye mbeu yekurapa., nzungu, donje, lawn uye zvirimwa zvakakosha, nezvimwewo, sezviyo, soya bhinzi, miti yemichero nemiriwo zvinokonzerwa neConcha, Botrytis cinerea, Powdery mildew, Cercospora, Puccinia, Rhizoctonia, Sclerotium Zvirwere zvinokonzerwa nemhango fungi, botrytis cinerea, ngura. , powdery mildew of legumes, cotton blight, sunflower and rapeseed zvirwere zvinokonzerwa neAlternaria, nezvimwewo. Yakanyoreswa kuti ishandiswe pazvirimwa zvinodarika makumi manomwe mugore ra2015, BASF ine chinangwa chekunyoresa kuti ishandiswe pazvirimwa zvinodarika zana.

Fluoxafen ine kuchinjika kwakasimba, uye kune akawanda marudzi ezvigadzirwa zvemusanganiswa.Adexar (fluconazole + epoxiconazole) inoshandiswa mugorosi, bhari, triticale, rye uye oats kudzora powdery mildew, leaf blight, glume blight, stripe rust uye leaf rust.Priaxor (flufenapyr + pyraclostrobin) yakanyoreswa muUnited States yesoyabhinzi, matomatisi, mbatatisi nezvimwe zvirimwa zvemumunda, uye ine zvakakosha pakutonga kwesoya bean brown spot (Septoria glycines);Orkestra SC (flufenapyr + Pyraclostrobin) yakanyoreswa muBrazil kune soya bhinzi, citrus, mbatatisi, hanyanisi, karoti, maapuro, mango, mavise, magaka, bhero mhiripiri, matomatisi, canola, nzungu, bhinzi dzeitsvo, maringazuva, mhunga, chibage, gorosi uye maruva (Chrysanthemum and rose), nezvimwewo, anogona kudzora ngura yesoya yeAsia, kuwedzera photosynthesis yezvirimwa, uye kushandiswa pakurwisa zvirwere.Priaxor D (flufenapyr + pyraclostrobin + tetraflufenazole) yakanyoreswa muUnited States kudzivirira nekudzora soyabean grey spot inoshingirira methoxyacrylate fungicides.Mushonga wekurapa mbeu Obvius (flufenapyr + pyraclostrobin + metalaxyl) wakanyoreswa kuUnited States uye unokwanisa kudzora zvirwere zvakasiyana siyana zvembeu zvezvirimwa zvakawanda.

Iyo succinate dehydrogenase inhibitor fungicides yakakura nekukurumidza mumakore achangopfuura, uye fluoxamid ndiyo inotungamira chigadzirwa cherudzi urwu rwefungicides, nekuda kwehunyanzvi hwayo hwepamusoro, yakakura spectrum, systemic chiitiko, yakakodzera kune dzakasiyana zvirimwa uye humwe hunhu Kunyanya, iyo inoenderera. kuvandudzwa kwezvigadzirwa zvayo zvakasanganiswa kwakawedzera hutongi hwezvimiro uye chiyero chezvirimwa zvakaiswa, uye chave parera rinopenya mumusika wefungicide.