Maitiro ekuita fluconazole

Fluoxapyr inonzi carboxamidefungicideyakagadzirwa neBASF. Iine mabasa akanaka ekudzivirira uye ekurapa. Inoshandiswa kudzivirira uye kudzora yakakura-spectrum fungal zvirwere, angangoita 26 marudzi ezvirwere zvefungal. Inogona kushandiswa zvirimwa zvingangosvika zana, sezvirimwa zvezviyo, nyemba, zvirimwa zvemafuta, nzungu, pome nematombo miti yemichero, midzi uye tuber miriwo, miriwo yemichero nedonje, mashizha kana mbeu kurapwa. Fluoxafenamide is succinate dehydrogenase inhibitor uye yakanakisa fungicide yakagadzirwa mumakore achangopfuura.
Physicochemical properties ye fluconazole

Fluconazole Chemical Name: 3-(difluoromethyl)-1-methyl-N-(3′,4′,5′-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide, 3-(difluoro Methyl) -1-methyl-N-(3′,4′,5′-trifluorobiphenyl-2-yl) -1H-pyrazole-4-carboxamide; Nhamba yeCAS: 907204-31-3, Molecular formula: C18H12F5N3O. Molecular uremu: 381.31 g/mol.Fluoxapyr (kuchena 99.3%) ichena kune beige yakasimba, isinganhuwi, inonyunguduka 156.8 ℃, hukama hwehukama (20 ℃) ​​1.42 g/mL, inoora paanenge 230 ℃, vapor pressure (inofungidzirwa): 2.7 × 20-10 × 9 Pax), (2.7 × 20-1 × 9) (25°C); Nguva dzose yaHenry: 3.028 × 10-7 Pa · m3 / mol. Solubility (20℃): mvura 3.88 mg/L (pH 5.84), 3.78 mg/L (pH 4.01), 3.44 mg/L (pH 7.00), 3.84 mg/L (pH 9.00); organic solvent (technical kuchena 99.2) %) (g/L, 20℃): acetone>250, acetonitrile 167.6±0.2, dichloromethane 146.1±0.3, ethyl acetate 123.3±0.2, methanol±0.40. n-octanol 4.69±0.1 , n-heptane 0.106 ± 0.001. n-octanol-water partition coefficient (20°C): deionized water log Kow 3.08, log Kow 3.09 (pH 4), log Kow 3.13 (pH 7), log Kow 3.09 (pH 9), avhareji yedanda Kow (3.10±0.02) . Yakagadzikana mune aqueous solution papH 4, 5, 7, 9 pasi perima uye sterile mamiriro. Kuvhenekera kwakagadzikana.

Toxicity yeFluoxafen

Acute oral toxicity mumakonzo (mukadzi) wepakutanga zvinodhaka fluconazole: LD50≥2,000 mg/kg, acute dermal toxicity mumakonzo (murume nemukadzi): LD50> 2,000 mg/kg, acute inhalation toxicity mumakonzo (murume nemukadzi): LC.51 mg/L; kushatirwa kuduku kumaziso etsuro uye ganda retsuro; hapana sensitization kune guinea pig ganda. Hapana carcinogenicity, hapana teratogenicity, hapana mhedzisiro pakubereka, hapana genotoxicity, neurotoxicity uye immunotoxicity.
Muchetura weshiri kushiri LD50＞2,000 mg/kg, huturu hweDaphnia 6.78 mg/L (48 h), huturu hwehove hunotyisa (96 h) LC50 0.546 mg/L, huturu hwezvipukanana zvemumvura (48 h) , EC50 EC50. (72 h) EC50 0.70 mg/L, acute kuonana muchetura kune nyuchi (48 h) LD50>100 μg/nyuchi, acute mukanwa muchetura kune nyuchi (48 h) LD50>110.9 μg/nyuchi, acute toxicity kune earthworms> 10 mg / 10 LC mazuva, 010 LC0. Kubva pane data iri pamusoro, zvinogona kuonekwa kuti Fluoxafen ine chepfu kune zvipenyu zvemvura uye ine yakaderera chepfu kune zvimwe zvipenyu zvinobatsira.

Nzira yekuita yefluoxafen

Fluoxafenamide is succinate dehydrogenase inhibitor, iyo inoshanda pa succinate dehydrogenase mumitochondrial breathing chain complex II kuvharidzira basa rayo, nokudaro ichidzivisa kumera kwefungal pathogen spores, kukura kwegerm tubes uye mycelium.

Fluconazole kudzora zvinhu

Fluoxamid inoshanda zvakanyanya, yakakura-spectrum, yakasimba, inosarudza, ine yakanakisa systemic conductivity, uye inoshingirira kukukurwa kwemvura. Inogona kunyatso kudzora zviyo, soya bhinzi, chibage, mhodzi dzechibharo, miti yemichero, miriwo, uye shuga beet kuburikidza nefoliar uye mbeu yekurapa. , nzungu, donje, lawn uye zvirimwa zvakakosha, nezvimwewo, zvakaita sembeu, soya bhinzi, miti yemichero nemiriwo zvinokonzerwa neConcha, Botrytis cinerea, Powdery mildew, Cercospora, Puccinia, Rhizoctonia, Sclerotium Zvirwere zvinokonzerwa nemhango fungi, botrytis cinerea, ngura, zvirwere zvepowdese mildew, sunflower. zvakakonzerwa neAlternaria, nezvimwewo. Yakanyoreswa kushandiswa pazvirimwa zvinodarika makumi manomwe panosvika 2015, BASF ine chinangwa chekunyoresa kuti ishandiswe pazvirimwa zvinodarika zana.

Fluoxafen ine kuchinjika kwakasimba, uye kune akawanda marudzi ezvigadzirwa zvemusanganiswa. Adexar (fluconazole + epoxiconazole) inoshandiswa mugorosi, bhari, triticale, rye uye oats kudzora powdery mildew, leaf blight, glume blight, stripe rust uye leaf rust. Priaxor (flufenapyr + pyraclostrobin) yakanyoreswa muUnited States yesoyabhinzi, matomatisi, mbatatisi nezvimwe zvirimwa zvemumunda, uye ine zvakakosha pakutonga kwesoya bean brown spot (Septoria glycines); Orkestra SC (flufenapyr + Pyraclostrobin) yakanyoreswa muBrazil kune soya bhinzi, citrus, mbatatisi, hanyanisi, makarotsi, maapuro, mango, mavise, magaka, bhero mhiripiri, madomasi, canola, nzungu, itsvo bhinzi, sunflowers, mhunga, chibage, gorosi uye maruva eAsia ngura, inovandudza photosynthesis yezvirimwa, uye kushandiswa pakudzivirira zvirwere. Priaxor D (flufenapyr + pyraclostrobin + tetraflufenazole) yakanyoreswa muUnited States kudzivirira nekudzora soyabean grey spot inoshingirira methoxyacrylate fungicides. Mushonga wekurapa mbeu Obvius (flufenapyr + pyraclostrobin + metalaxyl) wakanyoreswa kuUnited States uye unokwanisa kudzora zvirwere zvakasiyana siyana zvembeu zvezvirimwa zvakawanda.

Iyo succinate dehydrogenase inhibitor fungicides yakakura nekukurumidza mumakore achangopfuura, uye fluoxamid ndiyo inotungamira chigadzirwa cherudzi urwu rwefungicides, nekuda kwekushanda kwayo kwakanyanya, yakafara spectrum, systemic chiitiko, yakakodzera kune akasiyana zvirimwa uye humwe hunhu, Kunyanya, kuenderera mberi kwekugadzirwa kwezvigadzirwa zvayo zvemusanganiswa kwakawedzera hutongi hwekutonga uye chiyero chemusika chave zvirimwa zvinopenya.