Kusangana nemamwe makemikari anouraya zvipembenene, akadai semishonga inodzinga umhutu, kune chekuita nemhedzisiro yakaipa pahutano, zvichienderana neongororo yedata redzidzo yehurumende.
Pakati pevatori vechikamu muNational Health and Nutrition Examination Survey (NHANES), huwandu hwakawanda hwekusangana nemishonga yezvipembenene inoshandiswa pamba yakabatana nekuwedzera kwengozi yekufa nezvirwere zvemwoyo zvakapetwa katatu (hazard ratio 3.00, 95% CI 1.02–8.80) Dr. Wei Bao nevamwe vake vekuYunivhesiti yeIowa muIowa City vanoti.
Vanhu vari munzvimbo dzine njodzi huru yekuuraya zvipembenene izvi vaivawo ne56% yekufa nezvikonzero zvese zvichienzaniswa nevanhu vari munzvimbo dzine njodzi shoma yekuuraya zvipembenene izvi (RR 1.56, 95% CI 1.08–2. 26).
Zvisinei, vanyori vakataura kuti mishonga yezvipembenene inonzi pyrethroid haina chekuita nekufa kwekenza (RR 0.91, 95% CI 0.31–2.72).
Mamodheru akagadziriswa zvichienderana nerudzi/dzinza, murume kana mukadzi, zera, BMI, creatinine, kudya, mararamiro, uye zvinhu zvine chekuita nemagariro evanhu.
Mishonga yezvipembenene inonzi Pyrethroid inotenderwa kushandiswa neUS Environmental Protection Agency uye inonyanya kushandiswa mumishonga inodzinga umhutu, mishonga inodzinga inda mumusoro, shampoos dzezvipfuyo nemaspray, uye zvimwe zvigadzirwa zvekudzivirira zvipembenene mukati nekunze uye zvinoonekwa sezvisina njodzi.
"Kunyangwe mishonga yepyrethroids inodarika chiuru yakagadzirwa, kune mishonga yezvipembenene inosvika gumi nemaviri chete yepyrethroid iri pamusika weUS, yakaita sepermethrin, cypermethrin, deltamethrin uye cyfluthrin," chikwata chaBao chakatsanangura, vachiwedzera kuti kushandiswa kwemishonga yepyrethroids "kwakawedzera." "Mumakumi emakore achangopfuura, mamiriro acho ezvinhu akawedzera zvakanyanya nekuda kwekurega kushandiswa kwe organophosphates munzvimbo dzekugara."
Mumashoko anotevera, Stephen Stellman, Ph.D., MPH, naJean Mager Stellman, Ph.D., vekuColumbia University muNew York, vanoti mishonga yepyrethroids "ndiyo yechipiri inonyanya kushandiswa mishonga yezvipembenene pasi rose, inosvika zviuru zvemakirogiramu uye makumi emamiriyoni emadhora ekuAmerica." Kutengeswa kwemishonga yeUS mumadhora ekuAmerica.
Uyezve, “mishonga inouraya zvipembenene inonzi pyrethroid inowanikwa kwose kwose uye kupararira kwayo hakudzivisiki,” vanonyora kudaro. Haisi dambudziko revashandi vepapurazi chete: “Kupfapfaidza umhutu mudenga kudzora hutachiona hweWest Nile nezvimwe zvirwere zvinotapukira muNew York nedzimwe nzvimbo kunonyanya kushandiswa ne pyrethroid,” anodaro Stelmans.
Chidzidzo ichi chakaongorora mhedzisiro yevanhu vakuru vanopfuura 2,000 vakapinda muchirongwa cheNHANES che1999–2000 vakaongororwa muviri, vakatora ropa, uye vakapindura mibvunzo yeongororo. Kuonekwa kwePyrethroid kwakayerwa nemazinga e3-phenoxybenzoic acid muweti, metabolite yepyrethroid, uye vatori vechikamu vakakamurwa kuita tertiles dzekuonekwa kwechirwere.
Munguva yeavhareji yekutevera kwemakore gumi nemana, vanhu 246 vakafa: 52 nekenza uye 41 nechirwere chemwoyo.
Paavhareji, vanhu vatema vasiri vemuHispanic vaibatwa nezvirwere zvepyrethroids zvakanyanya kupfuura vanhu vemuHispanic nevachena vasiri vemuHispanic. Vanhu vane mari shoma, vane dzidzo yakaderera, uye vane kudya kwakashata ndivo vaibatwawo nezvirwere zvepyrethroids zvakanyanya.
Stellman naStellman vakaratidza "hafu yenguva pfupi" ye pyrethroid biomarkers, ichiita avhareji yemaawa 5.7 chete.
"Kuvapo kwehuwandu hwemasero epyrethroid anobviswa nekukurumidza mumapoka makuru, akasiyana-siyana enzvimbo kunoratidza kuti munhu anogara kwenguva refu uye kunoitawo kuti zvive zvakakosha kuziva nzvimbo chaiyo yezvakatipoteredza," vakadaro.
Zvisinei, vakataurawo kuti nekuda kwekuti vatori vechikamu muchidzidzo ichi vaive vadiki pazera (makore 20 kusvika 59), zvakaoma kufungidzira zvizere hukama huripo nerufu rwemwoyo.
Zvisinei, "mutengo wengozi huru usingawanzoitiki" unoda kutsvagurudzwa kwakawanda pamusoro pemakemikari aya uye njodzi dzawo dzinogona kuitika pahutano hwevanhu, Stellman naStellman vakadaro.
Chimwe chikanganiso chekudzidza uku, sekureva kwevanyori, kushandiswa kwemasampuli emuweti wemumunda kuyera metabolites dzepyrethroid, izvo zvingasaratidze shanduko nekufamba kwenguva, zvichikonzera kusarongeka kwekushandiswa kwemishonga yezvipembenene yepyrethroid nguva dzose.
Kristen Monaco munyori mukuru anonyanya kutaura nezve endocrinology, psychiatry uye nephrology. Anogara muhofisi yeNew York uye anga ari mukambani iyi kubvira muna 2015.
Tsvagiridzo iyi yakatsigirwa neNational Institutes of Health (NIH) kuburikidza neYunivhesiti yeIowa Environmental Health Research Center.
Nguva yekutumira: Gunyana-26-2023