Kuratidzira kune mamwe makemikari ezvipembenene, akadai seanodzinga umhutu, anosanganiswa neakaipa hutano mhedzisiro, maererano nekuongorora kwe federal study data.
Pakati pevatori vechikamu muNational Health and Nutrition Examination Survey (NHANES), mazinga akakwirira ekuratidzwa kwemishonga inowanzoshandiswa yemhuri yepyrethroid yakabatanidzwa nekatatu kuwedzera kwengozi yekufa kwechirwere chemwoyo (hazard ratio 3.00, 95% CI 1.02-8.80) Dr. Wei Bao uye vaanoshanda navo kubva kuYunivhesiti yeIowa muIowa City vanoshuma.
Vanhu vari munzvimbo yepamusoro-soro yekusangana nemishonga iyi zvakare vaive ne56% yakawedzera njodzi yekufa kubva kune zvese zvinokonzeresa zvichienzaniswa nevanhu vari yakaderera tertile yekusangana nemishonga iyi (RR 1.56, 95% CI 1.08-2. 26).
Zvisinei, vanyori vakacherechedza kuti pyrethroid insecticides yakanga isingabatanidzi nekenza yekufa (RR 0.91, 95% CI 0.31-2.72).
Mienzaniso yakagadziridzwa kurudzi / dzinza, zvepabonde, zera, BMI, creatinine, kudya, mararamiro, uye sociodemographic zvinhu.
Mishonga yePyrethroid inotenderwa kushandiswa neUS Environmental Protection Agency uye inonyanya kushandiswa mumishonga inodzinga umhutu, inodzinga inda dzemusoro, shampoo yemhuka uye masprayers, uye zvimwe zvinhu zvemukati nekunze zvekudzivirira zvipembenene uye zvinoonekwa sezvisina njodzi.
“Kunyangwe mapyrethroids anodarika chiuru akagadzirwa, pamusika wekuUS pane mishonga yekuuraya zvipembenene ingangoita gumi nembiri, yakaita sepermethrin, cypermethrin, deltamethrin necyfluthrin,” chikwata chaBao chakatsanangura, chichiwedzera kuti kushandiswa kwepyrethroids “kwawedzera.”"Mumakumi emakore achangopfuura, mamiriro ezvinhu akawedzera zvakanyanya nekuda kwekusiya zvishoma nezvishoma kushandiswa kweorganophosphates munzvimbo dzinogara vanhu.“
Mune imwe tsinhiro inobatanidzwa, Stephen Stellman, Ph.D., MPH, naJean Mager Stellman, Ph.D., veColumbia University muNew York, vanocherechedza kuti pyrethroids “ndiyo mushonga wezvipembenene wechipiri unonyanya kushandiswa munyika, unosvika zviuru makirogiramu uye makumi emamiriyoni mazana emadhora ekuAmerica. "Kutengeswa kweUS mumadhora ekuUS.“
Uyezve, “mishonga inouraya zvipembenene inonzi pyrethroid inowanikwa kwose kwose uye kuratidzirwa hakudzivisiki,” vanonyora kudaro.Harisi dambudziko kuvashandi vemumapurazi chete: “Kupfapfaidza mosquito mundege kudzora utachiona hweWest Nile nezvimwe zvirwere zvinotapuriranwa nemavhakitari muNew York nekumwewo kunovimba zvakanyanya nemapyrethroids,” anodaro Stelmans.
Chidzidzo ichi chakaongorora mhedzisiro yevanopfuura zviuru zviviri vatori vechikamu muchirongwa che1999-2000 NHANES avo vakaongororwa mumuviri, vakaunganidza sampuli dzeropa, uye vakapindura mibvunzo yeongororo.Pyrethroid exposure yakayerwa neurinary mazinga e3-phenoxybenzoic acid, pyrethroid metabolite, uye vatori vechikamu vakakamurwa kuita tertiles yekuratidzwa.
Munguva yekutevera kwekutevera kwemakore e14, vatori vechikamu 246 vakafa: 52 kubva kukenza uye 41 kubva kuhutano hwemwoyo.
Paavhareji, vatema vasiri veHispanic vainyanya kuratidzwa kune pyrethroids kupfuura Hispanics uye vasiri maSpanish vachena.Vanhu vane mari yakaderera, mazinga edzidzo yakaderera, uye yakaderera yemhando yekudya zvakare vanga vaine yakanyanya tertile yekuratidzwa kwepyrethroid.
Stellman naStellman vakasimbisa iyo "ipfupi hafu yeupenyu" yepyrethroid biomarkers, avhareji yemaawa 5.7 chete.
"Kuvapo kwematanho anoonekwa ekukurumidza kubviswa pyrethroid metabolites muhombe, nzvimbo dzakasiyana-siyana kunoratidza kuratidzwa kwenguva refu uye zvakare kunoita kuti zvive zvakakosha kuona chaiwo mabviro ezvakatipoteredza," vakadaro.
Zvisinei, vakacherechedzawo kuti nokuti vatori vechidzidzo vakanga vachiri vaduku muzera (20 kusvika kumakore 59), zvakaoma kuenzanisa zvakakwana hukuru hwekubatana nemoyo wekufa.
Nekudaro, iyo "hazard yakanyanya quotient" inobvumidza kutsvagisa kumakemikari aya uye nenjodzi dzinogona kuitika pahutano hweveruzhinji, Stellman naStellman vakadaro.
Chimwe chinodzikisira chidzidzo, maererano nevanyori, ndiko kushandiswa kwemasampuli weti yemumunda kuyera pyrethroid metabolites, iyo inogona kusaratidza shanduko nekufamba kwenguva, zvichikonzera kusarudzika kwemaitiro ekutapurwa kwepyrethroid pesticides.
Kristen Monaco munyori mukuru anonyanya kuita zve endocrinology, psychiatry uye nephrology nhau.Anogara muhofisi yeNew York uye anga aine kambani kubva 2015.
Tsvagiridzo iyi yakatsigirwa neNational Institutes of Health (NIH) kuburikidza neYunivhesiti yeIowa Environmental Health Research Center.
Nguva yekutumira: Sep-26-2023